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Lrrk2 (leucine rich repeat kinase 2) is a protein coding gene Aberrant expression of this gene in adult tissues is associated with tumorigenesis. Diseases associated with lrrk2 include parkinson disease 8, autosomal dominant and parkinson's disease.
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Function, proteins, disorders, pathways, orthologs, and expression. This gene encodes a transcription factor containing a pou homeodomain that plays a key role in embryonic development and stem cell pluripotency The encoded protein is believed to be an integral membrane protein involved in small molecule transport, specifically tyrosine, which is a precursor to melanin synthesis.
This receptor also functions as a receptor for the secondary bile acid, lithocholic acid.
Function, proteins, disorders, pathways, orthologs, and expression Complete information for alk gene (protein coding), alk receptor tyrosine kinase, including
